Aluminium toxicity arises in patients with chronic renal failure
(CRF) due to two reasons. Firstly, oral aluminium is used as a
phosphate binder and intestinal absorption may be enhanced in CRF.
Secondly, dialysis fluid may have a high aluminium content
although, more recently, this is a rare cause.
Request on ICE
Analysed by referral laboratory if specific criteria met
Requested by Consultant Renal Physicians for monitoring patients
on renal dialysis
No specific preparation required
Red top plain tube
Sample must be collected into a Red topped tube. Do not use
1. Collect blood into a plastic syringe
2. Remove and discard needle
3. Discharge blood into red top tube and recap.
4. Send to laboratory as soon as possible
Sent to referral laboratory (Royal Surrey County Hospital)
Aliquot and store at 4C
Causes for Rejection
Unlabelled or incorrectly labelled sample; not meeting specific
criteria for analysis. Aluminium is prone to contamination
and must be collected using plastic consumables. Glass and gel
separator tubes must be avoided.
Normal: Less than 0.4 µmol/L
Levels greater than 2.2 µmol/L indicates increased aluminium
Aluminium concentration in dialysis fluid should not exceed 1.1
To convert from µmol/L to ug/L multiply by 26.95