Antiphospholipid syndrome (venous and arterial thrombosis, stroke,
TIA and multiple-infarct dementia in the absence of other features
Recurrent foetal loss
Please note: Transient antibodies may be found
after viral infections. It is therefore important to send a repeat
sample after 12 weeks to confirm a diagnosis of anti phospholipid
syndrome. The patient should also be tested for the presence of
Lupus Anticoagulant (if the patient is not on anticoagulant
Detection of IgG and IgM autoantibodies against Cardiolipin with
added Beta 2 Glycoprotein 1.
Request via ICE
Assay performed daily; Monday to Friday.
It is essential to provide relevant clinical information.
All samples are generally sent to referral
laboratory within 3 working days of receipt in the laboratory.
The assay is performed daily; Monday to Friday.
Samples should be transported to the laboratory immediately
Aliquot and store at 4-8°C prior to testing and at -20°C or
below for up to 1 month after receipt.
Causes for Rejection
Unlabelled/inadequately labelled sample
Inadequately completed request form
Delay in sample reaching laboratory
Negative: < 10 PLU/mL
Equivocal: 10-40 PLU/mL
Positive: > 40 PLU/mL
The level of antibody in units is not directly related to the
severity of disease. However, weak positive results are of doubtful