Anti ds DNA
Double stranded DNA
'Lupoid' chronic active hepatitis
Please note: Elevated levels occur predominantly in SLE. They are
not found in other connective tissue disorders, or in all cases of
Detection of IgG autoantibodies against double stranded DNA
Request via ICE
Assay performed daily; Monday to Friday.
It is essential to provide relevant clinical information.
Only samples found to be ANA positive will be referred for ds DNA
testing unless clinical information suggests testing may be
The assay is performed daily; Monday to Friday.
Samples should be transported to the laboratory immediately
Aliquot and store at 4-8°C prior to testing and at -20°C or
below for up to 1 month after receipt.
Causes for Rejection
Unlabelled/inadequately labelled sample
Inadequately completed request form
Delay in sample reaching laboratory
Grossly haemolysed, icteric or lipaemic samples may interfere
with the assay and will be rejected.
Negative: <10 IU/mL
Equivocal: 10-15 IU/mL
Positive: >15 IU/mL
Samples are screened at a
dilution of 1:10