Pathology Handbook

Borrelia Serology


Lyme Disease

Test Includes

Detection of IgG and/or IgM antibodies to Borrelia burgdorferi, as appropriate according to the clinical information given

Request Form 

Request via ICE


On request during normal working hours; reference laboratory test (Southampton)

Patient Preparation


Specific Criteria

Please give detailed clinical information, including date of onset/contact with the suspected infection

Turnaround Time

Samples are sent to a reference laboratory (Southampton); results are usually available within 10 - 14 days


Serum, red or gold top (SST) tube


7 ml


Vacutainer red top


Samples should be transported to laboratory immediately

Causes for Rejection

Unlabelled / inadequately labelled sample
Insufficient clinical information given

Reference Range


Lab Handling

Aliquot and store at 4°C; store at -40°C for 3 months after testing.  Send to Reference laboratory (Southampton) as soon as possible