Pathology Handbook

C3 Complement

Synonyms

-

Clinical Indications

C3 (and C4) is useful in investigation of patients with renal disease, joint disease and multi-system disorders with evidence of vasculitis, since low concentrations would imply an immunological basis for the symptoms. Complement levels may also be useful in patients with recurrent infections with normal or raised immunoglobulin levels, since genetic and acquired defects sometimes present as immunodeficiency (CH50 analysis also required in such cases).

Request Form

Request on ICE

Availability

On request

Turnaround Time

5 days

Specimen

Serum

Volume

2 ml

Container

Vacutainer gold top

Causes for Rejection

Unlabelled or incorrectly labelled sample

Reference Range

0.75 - 1.65 g/L