Pathology Handbook

Calcium

Clinical Indications

Hypercalcaemia is often discovered incidentally. There are no specific clinical features. Any of the following may occur: abdominal pain, renal/ureteric colic (due to calculi), bone pain, thirst and polyuria. Hypocalcaemia can cause paraesthesiae, muscle cramps and spasm.

Part of Profile

Bone profile

Request Form

Request on ICE

Availability

On request. Available urgently.

Turnaround Time

Same day

Specimen

Serum

Volume

2 ml

Container

Vacutainer gold top

Collection

Stasis during venepuncture will falsely elevate results. Samples for further investigation of mild hypercalcaemia should be taken fasting.

Correction for albumin levels

Calcium is corrected for albumin as follows:
'Adjusted calcium' = measured calcium + [0.02 x (42 - Albumin)] 

Causes for Rejection

Unlabelled or incorrectly labelled sample

Reference Range

Adjusted calcium reference ranges:

Adult: 2.20 - 2.60 mmol/L

Children:

Up to 14 days: 1.9 - 2.8 mmol/L

2 weeks to 6 months: 2.0 - 2.8 mmol/L

6 months to 1 year: 2.3 - 2.7 mmol/L

1-2 years: 2.3 - 2.65 mmol/L