Cardiac Muscle Antibodies
Dressler's syndrome post myocardial infarct (MI)
Please note: These antibodies have also been found in
patients with myocarditis, dilated cardiomyopathy and rheumatic
The detection of IgG autoantibodies against adenine nucleotide
translocator protein, cardiac myosin and tropomyosin.
Request via ICE
Assay is performed weekly.
It is essential to provide relevant clinical information.
No special preparation is required.
All samples are generally sent to referral
laboratory within 3 working days of receipt in the
laboratory. Samples are batched and the assay is performed twice
Serum in red top tube
Gold top (SST) tube will be accepted
Samples should be transported to the laboratory as soon as is
Aliquot and store at 4-8°C prior to testing and at -20°C or
below for up to 1 month after receipt.
Causes for Rejection
Unlabelled/inadequately labelled sample.
Inadequately completed request form.
Delay in sample reaching laboratory.
Samples are tested for the presence of anti Cardiac Muscle
antibodies by indirect immunofluorescence and the result reported
as Positive or Negative.