Cyclic Citrullinated Peptide
Rheumatoid Arthritis (RA)
Please note: This assay is very specific (>95%) and
sensitive (60 - 77%) for RA. It can aid early diagnosis, especially
in patients with undifferentiated arthritis, and the presence of
these antibodies is linked with a more aggressive disease.
Detection of IgG antibodies directed against a number of
citrulllinated synthetic peptides.
Request via ICE
Assay performed daily Monday to Friday.
It is essential to provide relevant clinical information.
No special preparation is required.
All samples are generally sent
to referral laboratory within 3 working days of
receipt in the laboratory. Samples are batched and the assay is
performed twice per week.
Serum in red top tube
Gold top (SST) tube will be accepted
Samples should be transported to the laboratory as soon as is
Aliquot and store at 4°C prior to testing and at -20°C or below
for 3 months after receipt.
Causes for Rejection
Unlabelled/inadequately labelled sample.
Inadequately completed request form.
Delay in sample reaching laboratory.
Negative: <7 U/mL
Equivocal: 7 - 10 U/mL
Positive: >10 U/mL