Low Density Lipoprotein Cholesterol
Cholesterol circulates in blood bound to lipoproteins; the two
main ones being low density lipoprotein (LDL) and high density
lipoprotein (HDL). High levels of LDL are associated with a
high risk of coronary disease.
Part of Profile
Request on ICE or use combined Biochemistry/Haematology form
Patients must fast for 10 hours prior to blood collection (for
follow up tests diabetic patients may not need to fast, but levels
may be decreased as a result of recent food intake).
Causes for Rejection
Unlabelled or incorrectly labelled sample
The concept of a reference range is flawed and acceptable levels
depend on presence of other coronary risk factors. For patients
with established coronary disease or diabetes, LDL cholesterol
levels should be less than 3.0 mmol/L..
LDL cholesterol is a calculated from other lipid
parameters. It should be remembered that the variability in
measurement of these individual parameters is compounded in the LDL
calculation and that small changes in LDL (<0.5 mmol/L) are
LDL cannot be calculated when triglyceride levels are > 4.5
LDL Cholesterol = Total Cholesterol - HDL Chol - (Triglycerides