Cotinine levels are raised in the blood and urine of smokers.
Levels may therefore indicate whether someone is smoking (very high
levels) or whether they have been exposed to passive smoking (lower
Please use handwritten Biochemistry request form
Samples should be taken less than 48 hours after the patient has
been exposed to smoke; after intervals longer than this, levels
will decline to the 'non-smoking' range.
Urine in white-top universal
minimum 2ml of urine or serum.
Sent to referral laboratory (Llandough Toxicology lab)
Samples should be stored at 4oC until dispatch
Causes for Rejection
Unlabelled or incorrectly labelled sample; not meeting specific
criteria for analysis; delay in sample reaching laboratory or in
wrong sample container
See reference laboratory report for interpretation of