Pathology Handbook

Electrophoresis (serum)

Synonyms

SPE, EPS, SEP

Clinical Indications

  • Investigation and monitoring of myeloma, and other B cell dyscrasias.

  • Investigation of high serum globulin level

  • Suspicion of abnormal alpha-1 antitrypsin.

Part of Profile

Automatically done when immunoglobulin levels are requested on an adult; reflex request if patient has globulin level >38g/L

Request Form

Request on ICE

Availability

On request

Specific Criteria

None

Turnaround Time

Two days

Specimen

Serum

Volume

2 ml

Container

Vacutainer gold top

Lab Handling

Aliquot and store at 4°C

Causes for Rejection

Unlabelled or incorrectly labelled sample; assay within previous month; plasma sample

Interpretation

An interpretative report issued.

Further investigations will be performed if an abnormal band is found - confirmation, identification and quantitation.