Pathology Handbook

Ganglioside antibodies - GQ1b

Clinical Indications (specialist request only)

Miller-Fisher Syndrome

Please note: Antibodies to GQ1b are found in 90-100% of patients with Miller-Fisher Syndrome.

Test Includes

Detection of IgG and IgM antibodies against the ganglioside GQ1b.

Request Form 

Request via ICE

Availability

Assay performed as required.

Specific Criteria

It is essential to provide relevant clinical information.

Patient Preparation

No special preparation is required.

Turnaround Time

All samples are generally sent to referral laboratory within 3 working days of receipt in the laboratory. Assay is performed as required

Specimen

Serum in red top tube

Gold top (SST) tube will be accepted

Volume

7 ml

Container

Vacutainer red top

Collection

Samples should be transported to the laboratory as soon as is practicably possible.

Causes for Rejection

Unlabelled/inadequately labelled sample

Inadequately completed request form

Delay in sample reaching laboratory.

Laboratory Handling 

Aliquot and store at 4-8°C prior to testing and at -20°C or below for up to 1 month after receipt.

Reference Range

Samples are tested for the presence of anti GQ1b antibodies by Enzyme Immunoassay and the results reported as Positive or Negative.