Haemoglobin S (sickle) screen
Sickledex, Sickle Sol, Sickle Solubility Test, HBS
To confirm or exclude presence of Haemoglobin S in cases of
urgent clinical need prior to surgery etc
Request on ICE
The test will be performed on urgent requests (pre-op) where
there is insufficient time to perform HPLC. Contact the laboratory
to arrange urgent testing.
Ethnic origin required
Purple top (EDTA)
Bring to laboratory as soon as possible after collection
Causes for Rejection
Incorrect sample labelling/ clotted sample/ haemolysis .
This test is not reliable on :
i) infants less than 6 months old
ii) in the presence of abnormal levels of serum protein, extreme
leucocytosis and hyperlipidaemia.
HPLC will be performed on all requests for Sickle test. Hb
variants requiring confirmation may be sent to Reference