HCG (tumour marker)
Human Chorionic Gonadotrophin (HCG)
HCG levels are useful as a diagnostic aid and for monitoring
treatment in some maligancies:
- Virtually all patients with gestational trophoblastic disease
(GTD) i.e. molar pregnancy, choriocarcinoma and placental site
- Non-seminomatous germ cell tumours (NSGCT) e.g. of testis and
Request on ICE
On request if specific criteria met.
Diagnostic aid and for monitoring patients with GTD and (in
conjunction with AFP) a diagnostic aid and for monitoring patients
with NSGCT of testis, ovary and other sites.
HCG should not be used for monitoring other malignancies.
Causes for Rejection
Unlabelled or incorrectly labelled sample; not meeting specific
criteria for analysis.
< 5 U/litre
Half-life in Serum
Approx. 16 - 24 hours, decline may be biphasic with a second
half-life of 12.8 days.
There are very few benign conditions associated with elevated
HCG levels e.g. pituitary adenoma.
HCG levels are elevated in pregnancy.