Pathology Handbook

Hepatitis B core antibody

Synonyms

HBCT

Clinical Indications

To confirm naturally-acquired immunity to Hepatitis B

Often requested alongside Hepatitis B surface antigen to rule out current or previous infection in non-responders to Hepatitis B vaccine

Test Includes

Detection of core IgG and IgM antibodies

Request Form

ICE request

Availability

On request during routine working hours

Specific Criteria

Please give detailed clinical information including date of contact with infection

Turnaround Time

Tests usually performed on next routine working day after receipt of sample

Specimen

Serum, red or gold top (SST) tube

Volume

7 ml

Container

Vacutainer red top

Collection

Samples should be transported to laboratory immediately

Causes for Rejection

Unlabelled / inadequately labelled sample
Delay in sample reaching laboratory

Lab Handling

Aliquot and store at 40°C prior to testing; store at -40°C for 3 months following testing