Homocysteine (for thrombotic tendency)
- Premature cardiovascular disease
- Thrombotic tendency
- Possible B12/folate deficiency
Request on ICE
Analysed by referral laboratory if specific criteria met.
Agreed with Consultant Biochemist.
Patient should be fasting as homocysteine levels may increase
EDTA Plasma in lemon-top tube
2 ml minimum
Sample must be transported to laboratory and separated within 30
minutes of collection
Patients must be bled at Southend Hospital.
Sent to referral laboratory (Guy's Hospital)
Causes for Rejection
Unlabelled or inadequately labelled sample.
Delay in transit to laboratory.
Less than 17 mmol/l
Raised levels may indicate a genetic disorder or sulphur amino
acid metabolism and/or B12/folate deficiency. Raised levels are
reported to be a risk factor for premature cardiovascular disease
and/or clotting tendency.