Pathology Handbook

Intrinsic Factor Antibody

Synonyms

IFA

IF

Clinical Indications

Pernicious Anaemia

All requests for a Pernicious Anaemia Screen will be tested for the presence of gastric parietal cell antibodies and Intrinsic factor antibodies.

Test Includes

Detection of IgG autoantibodies against Intrinsic Factor.

Request Form 

Request via ICE.

Availability

Assay is performed weekly, usually on a Wednesday.

Specific Criteria

It is essential to provide relevant clinical information.

Patient Preparation

No special preparation is required.

Turnaround Time

Samples are tested weekly.

Specimen

Red top tube.

Gold top tube will be accepted. 

Volume

7 ml

Container

Vacutainer red top

Collection

Samples should be transported to the laboratory as soon as is practicably possible.

Lab Handling

Aliquot and store at 4-8°C prior to testing and at -20°C or below for up to 1 month after receipt.

Causes for Rejection

Unlabelled/inadequately labelled sample

Inadequately completed request form

Delay in sample reaching laboratory.

Reference Range

Results are reported as Positive, Negative or Equivocal.