Pathology Handbook




Clinical Indications

The main use for this test is in the investigation of iron overload, when the transferrin saturation should also be assessed.

Measurement of serum iron is of little relevance in the investigation of iron deficiency; levels fall during acute infection (e.g. a cold); in patients taking oral iron (or multivitamins) levels reflect recent intake and are not representative of the true physiological state

Part of Profile

Transferrin saturation

Request Form 

Request on ICE


On request specific criteria are met

The test will not be done if relevant clinical details are not provided

Specific Criteria

Investigation of iron overload

Requested by Consultant Haematologist

Patient Preparation

None; fasting samples give more reliable results

Turnaround Time

Same day


Serum in gold top (SST) tube


2 mL


Vacutainer gold top

Causes for Rejection

Unlabelled sample
Not meeting specific criteria for analysis.  

Reference Range

10-30 ┬Ámol/L