Ovary/Testis Steroid Cell Antibody
Premature ovarian failure
Please note: This assay includes the detection of
antibodies to adrenal cortex; parathyroid gland; pituitary gland;
ovary and testes. Autoantibodies against steroid producing cells
are found in 50-70% of patients with Addison's disease; 30-70% of
patients with premature ovarian failure; 60-80%of patients with
autoimmune polyglandular disease (AGPS) Type 1; 40-80% of patients
with AGPS type 2 and approximately 11% of patients with AGPS type
Detection of IgG antibodies against cytochrome P450 enzymes
Request via ICE
Assay is performed twice weekly.
It is essential to provide relevant clinical information.
No special preparation is required.
All samples are generally sent to referral
laboratory within 3 working days of receipt in the
laboratory. Samples are batched and the assay is performed twice
Serum in red top tube
Gold top (SST) tube will be accepted
Samples should be transported to the laboratory as soon as is
Aliquot and store at 4-8°C prior to testing and at -20°C or
below for up to 1 month after receipt.
Causes for Rejection
Unlabelled/inadequately labelled sample
Inadequately completed request form
Delay in sample reaching laboratory.
A qualitative result is given and samples are reported as
Positive or Negative.