Differential diagnosis of hypercalcaemia.
Assessment of parathyroid activity in patients with chronic renal
Investigation and monitoring of patients with hyperparathyroidism
secondary to vitamin D deficiency or malabsorption.
Investigation of hypocalcaemia.
Request on ICE
On request, if specific criteria met.
Investigation of abnormal calcium status or monitoring renal
Samples must only be collected at Southend Hospital
Calcium levels should be requested at same time.
EDTA plasma (Biochemistry EDTA) and a serum SST sample
Samples should be transported to the laboratory as soon as
possible after collection.
Sample must be separated and frozen as soon as possible after
Causes for Rejection
Delay in sample reaching laboratory. Unnecessary repeat
1.05 - 6.83 pmol/L for normocalcaemic patients.
However, most patients are being investigated for abnormal
calcium levels and in non-parathyroid disease PTH levels should
reflect calcium status (i.e. high calcium, low PTH).
In the presence of hypercalcaemia, a clearly elevated PTH of
>7.0 pmol/L is diagnostic of primary hyperparathyroidism, while
an appropriately suppressed result of <2.6 pmol/L virtually
excludes primary hyperparathyroidism but could be due to FBH.
Where the PTH is between 2.6 and 7.0 pmol/L, either primary
hyperparathyroidism or FBH is possible.