Polymyositis/scleroderma overlap syndrome
(Specialist request only)
Please note: This autoantibody may also be
found in patients with dermatomyositis/polymyositis or systemic
sclerosis occurring alone.
Detection of IgG antibodies to a complex of 11 cell
Request on ICE
Assay is performed as required.
No special preparation is required.
It is essential to provide relevant clinical information.
All samples are generally sent to referral
laboratory within 3 working days of receipt in the
laboratory. The assay is performed as required.
Red top tube. Gold top tube will be accepted.
Samples should be transported to the laboratory as soon as is
Aliquot and store at 4-8°C prior to testing and at -20°C or
below for up to 1 month after receipt.
Causes for Rejection
Unlabelled/inadequately labelled sample.
Inadequately completed request form.
Delay in sample reaching laboratory.
A qualitative result is given and samples are reported as
Positive or Negative.