Pathology Handbook

hs-Troponin T


cTnT, Trop T, TnT

Clinical Indications

hs-Troponin T is a regulatory protein that helps heart muscle contract and is released into blood when cell damage occurs. Its use is in further investigation and risk stratification of patients with chest pain of undiagnosed origin.

Request Form

Request on ICE



Specific Criteria

Sample must be taken at least 12 hours after admission (or after onset of clearly defined chest pain) and within 72 hours. A decision to request Troponin T will usually be made during the post-take ward round.

Turnaround Time

Same Day


Serum in yellow top (SST) tube; lithium heparin samples are acceptable


2 ml


Vacutainer gold top

Causes for Rejection

Not meeting specific criteria for analysis. Haemolysed sample.

Reference Range

A cut-off level of 0.05 ug/L is used. Providing the sample has been taken at the appropriate time, patients with levels below this have undetectable cardiac damage and are identified as low risk.